Originally from Kerala, Anuradha Menon grew up in Chennai. Her parents Mini and Mohan Menon worked in the advertising industry. Anuradha Menon started taking part in theatre productions in school. She was associated with The Madras Players for some years. In 2000, she played Shubra in Madras Players' Lizard Waltz (written by Chetan Shah and directed by Bhagirathi Narayanan). She also studied theatre at a school in London for one year, London school of drama. Then, she moved to Mumbai as it was the hub of English theatre in India.
